Table 4.
Multivariate cox analysis for incident chronic kidney disease (CKD) by level of body mass index in young adults.
| Group | Total (n) | CKD (n) |
% | HR (95% Confidence Interval) | |||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 4 | ||||
| Body mass index 5 level | |||||||
| <18.5 | 190,346 | 179 | 0.09 | 0.690 (0.592–0.804) |
0.863 (0.740–1.007) |
0.876 (0.751–1.023) |
0.901 (0.771–1.052) |
| 18.5~23 | 1,360,230 | 1854 | 0.14 | 1(Ref.) | 1(Ref.) | 1(Ref.) | 1(Ref.) |
| 23~25 | 634,091 | 1235 | 0.19 | 1.43 (1.330–1.537) |
1.278 (1.187–1.376) |
1.269 (1.179–1.367) |
1.138 (1.057–1.227) |
| 25~30 | 729,510 | 2107 | 0.29 | 2.122 (1.994–2.259) |
1.830 (1.713–1.955) |
1.84 (1.722–1.965) |
1.368 (1.277–1.465) |
| 30~ | 116,707 | 478 | 0.41 | 3.013 (2.724–3.332) |
2.816 (2.540–3.120) |
2.855 (2.576–3.163) |
1.550 (1.391–1.727) |
| p for trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 | |||
| Obesity (Body mass index ≥25) | |||||||
| <25 | 2,184,667 | 3268 | 0.15 | 1(Ref.) | 1(Ref.) | 1(Ref.) | 1(Ref.) |
| ≥25 | 846,217 | 2585 | 0.31 | 2.045 (1.942–2.154) |
1.789 (1.695–1.888) |
1.802 (1.707–1.902) |
1.323 (1.25,0–1.400) |
| p for trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 | |||
Abbreviations. CKD, chronic kidney disease; HR, hazard ratio. Model 1: non-adjusted. Model 2: adjusted for age, sex. Model 3: adjusted for model 2 plus smoking, alcohol drinking, regular exercise, income. Model 3: adjusted for model 3 plus glomerular filtration rate, hypertension, diabetes mellitus, dyslipidemia.