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. 2021 Mar 6;13(5):1136. doi: 10.3390/cancers13051136

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Two extracts of the hierarchically clustered heatmap of the 200 top expressed genes within all 12 cancer stem-like cell (CSC) populations. (A) Expressions of ribosomal biosynthesis associated genes were upregulated in endometrioid cancer stem-like cells c (ECSCs_c) and in prostate cancer stem-like cells b (PCSCs_b). Genes encoding for the S100 family were significantly expressed in all CSCs. (B) Expression levels of further genes relevant for ribosome biosynthesis differed between analyzed CSC populations, whereas glioblastoma stem-like cells b (GSCs_b) depicted the highest levels of genes responsible for the 40S and 60S subunit.