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Escin suppresses the nuclear translocation of p65 induced by TNF-α. The BxPC-3, AsPC-1 and SW1990 cell lines were initially treated with escin (10 µM) for 2 h, then stimulated with TNF-α (1 ng/ml) for 15 min before the end of incubation. Magnification; ×100. Ab, antibody; NF-κB, nuclear factor-κB; TNF, tumor necrosis factor.
