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. 2021 Mar 9;45(5):55. doi: 10.3892/or.2021.8006

Figure 5.

Figure 5.

Escin suppresses the secretion of IL-8 and VEGF in the PaCa cells. (A) BxPC-3 and SW1990 cell lines were cultured and treated with TNF-α for 48 h in the presence of escin. *P<0.05. (B) BxPC-3 and SW1990 cell lines were incubated for 48 h in the presence of various doses of escin. *P<0.05 vs. 0 µM. The concentrations of IL-8 and VEGF in the cell supernatants were measured with ELISA kits. VEGF, vascular endothelial growth factor; IL, interleukin.