Table 3.
Source and Time Point | Patient 2 | Patient 3 | Patient 4 | Patient 6 | Patient 7 | Patient 8 |
---|---|---|---|---|---|---|
Peripheral blood | ||||||
1.5 mo | ||||||
Whole blood | 0.89 | 2.11 | 0.82 | 1.66 | 1.49 | 1.23 |
CD19+ | 0.003 | 0.02 | 0.03 | 0.03 | 0.06 | 0.03 |
GlyA+, CD71+* | 0.47 | 2.39 | 1.31 | 1.02 | 1.38 | 1.07 |
3 mo | ||||||
Whole blood | 0.53 | 1.62 | 0.65 | 1.51 | 1.14 | 0.64 |
CD19+ | 0.3 | 1.2 | 0.48 | 1.11 | 0.68 | 0.55 |
GlyA+, CD71+ | 0.33 | 2.79 | 1.03 | 1.86 | 0.88 | 0.90 |
6 mo | ||||||
Whole blood | 0.42 | 1.49 | 0.61 | 1.19 | 1.04 | 0.69 |
CD19+ | 0.5 | 1.21 | 0.5 | 1.13 | 0.66 | 0.64 |
GlyA+, CD71+ | 0.2 | 2.85 | 0.96 | 1.35 | 0.76 | 0.68 |
Most recent time point† | ||||||
Whole blood | 0.30 | 1.61 | 0.63 | 1.11 | 1.03 | 0.69‡ |
CD19+ | 0.43 | 1.37 | 0.61 | 1.11 | 0.78 | 0.64‡ |
GlyA+, CD71+ | 0.23 | 1.99 | 0.77 | 1.95 | 1.39 | 0.68‡ |
Bone marrow | ||||||
6 mo | ||||||
CD34+ | 0.53 | 1.52 | 0.60 | 1.20 | 0.86 | 0.59 |
CD15+ | 0.65 | 1.59 | 0.79 | 1.65 | 1.25 | 0.77 |
GlyA+, CD71+ | 0.63 | 1.62 | 0.80 | 1.42 | 1.34 | 0.73 |
CD19+ describes B-lymphoid cells, and GlyA+, CD71+ describes erythroid precursors.
Data are the most recent values available with vector copy number lineage sorting before the October 2020 data snapshot (range, 6 to 24 months).
Month 6 was the most recent time point for Patient 8.