Table 2.

Examination strategy for sex steroid supplementation in PWS patients at our institution.

		at Start	after 1 Year	after 2 Years	Long Term, Every 2 Years
Boys	Clinical	Ht, Wt, PubSt, behaviour 1	Ht, Wt, PubSt, behaviour 1	Ht, Wt, PubSt, behaviour 1	Ht, Wt, PubSt, behaviour 1
	Lab	LH, FSH, T, E2, inhibin B, Hb, Hct	T, E2, Hb, Hct	LH, FSH, T, E2, inhibin B, Hb, Hct	T, E2, Hb, Hct
	Bone age	+	+	+	+ 2
	DXA	+		+	+ 3
Girls	Clinical	Ht, Wt, PubSt, behaviour 1	Ht, Wt, PubSt, behaviour 1	Ht, Wt, PubSt, behaviour 1	Ht, Wt, PubSt, behaviour 1
	Lab	LH, FSH, T, E2, inhibin B, AMH, liver panel	LH, FSH, T, E2, inhibin B, liver panel	LH, FSH, T, E2, inhibin B, liver panel	LH, FSH, T, E2, inhibin B, AMH, liver panel
	Bone age	+	+	+	+ 2
	DXA	+		+	+ 3

¹ Behavioural scale to be developed, simple instrument to objectively measure behaviour. ² until final height. ³ from age = 30 years every 5 years. AMH, anti-Müllerian hormone; DXA, Dual-energy X-ray absorptiometry; E2, oestrogen; FSH, follicle stimulating hormone; Hb, haemoglobin; Hct, haematocrit; Ht, height; LH, luteinising hormone; PubSt, pubertal stage; T, testosterone; Wt, weight.