Table 1.

GEE (generalized estimation equation) model with blood pressure, heart rate, or tail temperature as the dependent variable, and sex, vapor condition, and time as independent factors

Variables in the model	W	gl	p
Blood pressure
Sex	4.996	1	0.025	*
Vapor condition	5.795	1	0.016	*
Time	806.670	14	< 0.001	*
Sex × vapor	3.086	1	0.079
Sex × time	155.382	14	< 0.001	*
Vapor × time	42.638	14	< 0.001	*
Sex × vapor × time	96.417	14	< 0.001	*
Heart rate
Sex	0.167	1	0.683
Vapor condition	1.304	1	0.253
Time	447.653	14	< 0.001	*
Sex × vapor	0.003	1	0.955
Sex × time	116.907	14	< 0.001	*
Vapor × time	88.871	14	< 0.001	*
Sex × vapor × time	62.33	14	< 0.001	*
Tail temperature
Sex	0.854	1	0.355
Vapor condition	0.033	1	0.857
Time	42.697	6	< 0.001	*
Sex × vapor	0.195	1	0.659
Sex × time	14.260	6	0.027	*
Vapor × time	2.746	6	0.840
Sex × vapor × time	6.353	6	0.385

*p < 0.05