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Evaluation of tumor microenvironment (TME) differences between progressors (red), non-progressors (green), and animals from vehicle group (blue), from MCA205 study 1. (A) Simulated tumor size dynamics. Lines—median prediction, area—90% prediction interval (PI). (B) Density of simulated model parameters. (C) Simulated dynamics; and (D) boxplots of TME components at baseline and on day 14th day of treatment.
