Table 1.

Main findings

	DEP effect	Exercise effect	Interaction effect
Early ventilatory response	–	Altered breathing pattern	–
Airway hyperreactivity	–	↓	–
Airway inflammation
BAL Neutrophils	↑	–	–
DC recruitment
CD11b+CD103− DC	↑	–	–
moDC	↑	–	–
Airway permeability
Serum SP-D	↑	↑	↑↑
Serum Uric Acid	–	↑	–
BAL protein levels	–	–	–
Airway integrity
OCLN mRNA expression	↓	–	–
ZO-1 mRNA expression	↓	–	–
Cldn-1 mRNA expression	↑	–	–
Cldn-3 mRNA expression	–	↑	–
Cldn-4 mRNA expression	–	–	–
Cldn-18 mRNA expression	–	↑	–

Table 1 shows the major changes induced by DEP exposure (independently from exercise), by exercise (independently from DEP exposure) and by the interaction between DEP exposure and exercise. ↑ represents a significant increase in comparison to the non-exposed or non-exercised groups and ↓ represents a significant decrease in comparison to the non-exposed or non-exercised groups