Table 1.
Age Group | Prevaccinea (Jan 2009-Mar 2012) | Year 1 Postvaccine (Apr 2012-Mar 2013) | Year 2 Postvaccine (Apr 2013-Mar 2014) | Year 3 Postvaccine (Apr 2014-Dec 2014) | Total Postvaccine (Apr 2012-Dec 2014) |
---|---|---|---|---|---|
<1 y | |||||
RV+/No. (%) | 852/1688 (50) | 65/251 (26) | 60/211 (28) | 34/140 (24) | 159/602 (26) |
RV rate reductiona,b (95% CI) | 1 | 58% (43%−70%) | 63% (45%−74%) | 73% (55%−84%) | 56% (38%−69%) |
AGE rate reductionb (95% CI) | 1 | 51% (30%−65%) | 57% (20%−76%) | 52% (−18% to 80%) | 52% (36%−64%) |
1 to <2 y | |||||
RV+/No. (%) | 386/820 (47) | 50/186 (27) | 51/151 (34 | 29/84 (35%) | 130/421 (32) |
RV rate reductiona,b (95% CI) | 1 | 43% (15%−62%) | 29% (−26% to 60%) | 31% (−57% to 70%) | 44% (21%−60%) |
AGE rate reductionb (95% CI) | 1 | 30% (0%−51%) | 42% (−3% to 68%) | 51% (−16% to 80%) | 23% (−4% to 44%) |
2 to <5 y | |||||
RV+/No. (%) | 81/252 (32) | 11/46 (24) | 17/49 (35) | 10/51 (20) | 38/146 (26) |
RV rate reductiona,b (95% CI) | 1 | 38% (−43% to 73%) | 29% (−173% to 76%) | 56% (−141% to 92%) | 19% (−70% to 61%) |
AGE rate reductionb (95% CI) | 1 | 30% (−18% to 60%) | 9% (−123% to 63%) | 80% (−552% to 50%) | 50% (22%−68%) |
Total (<5 y) | |||||
RV+/No. (%) | 1319/2760 (48) | 126/483 (26) | 128/411 (31) | 73/275 (27) | 327/1169 (28) |
RV rate reductiona,b (95% CI) | 1 | 54% (38%−65%) | 52% (30%−66%) | 64% (42%−87%) | 49% (32%−63%) |
AGE rate reductionb (95% CI) | 1 | 43% (20%−43%) | 48% (9%−71%) | 43% (−30% to 75%) | 44% (28%−64%) |
Vaccine was introduced nationally in April 2012.
Abbreviations: AGE, acute gastroenteritis; CI, confidence interval; RV, rotavirus.
Komfo Anokye Teaching Hospital rotavirus testing data were excluded from 2009 analysis.
Compared to prevaccine period, adjusting for hospital and calendar month and secular time trends.