Fig. 3.

The heatmap generated using intraocular pressure elevation in open-angle glaucoma-related single nucleotide polymorphisms in the East Asian population. The heatmap shows how significantly the effect alleles are enriched or depleted in each population. Each row shows SNPs, and each column shows populations of diverse ancestry. Red color means effect allele is enriched, whereas purple color means effect allele is depleted (log₁₀ P > 1.301 indicated enrichment, log₁₀ P <  − 1.301 indicated depletion). A hierarchical clustering tree shows the differences among East Asians, KOR, JPT, and CHB in one cluster, and CHS, and CDX in another cluster. CDX: Chinese Dai in Xishuangbanna, CHB: Han Chinese in Beijing, China, CHS: Southern Han Chinese, China, JPT: Japanese in Tokyo, Japan, KOR: Korean in Republic Korea, KHV: Kinh in Ho Chi Minh City, Vietnam