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Inhibition of in-vitro angiogenesis and capillary tube formation by soluble FGFR-1 receptors. Phase-contrast images of ABAE cells forming three-dimensional capillary structures (arrows) in collagen gels grown with FGF-2 (500 pg) in the absence (A) or presence (B) of the secreted FGFR-1 receptor (300 ng). Bar = 200 um. Panels (C,D) show the corresponding capillary tube structures highlighted in red. (E) The area of capillary tube formation was quantified using ImageJ.
