AD	atopic dermatitis
AJCC	American Joint Committee on Cancer
AJCC8	8th Edition of AJCC staging system
AK	actinic keratosis
BCC	Basal cell carcinoma
BM	bone marrow
BWH	Brigham and Women’s Hospital
CDKN2A	cyclin-dependent kinase inhibitor 2A
CE	cornified cell envelope
CFC	Cardio-Facio-Cutaneous
CHS	contact hypersensitivity
CIB1	calcium and integrin binding 1
cSCC	cutaneous squamous cell carcinoma
CTL	cytotoxic T lymphocytes
CTLA-4	cytotoxic T-lymphocyte antigen 4
CXCR	C-X-C chemokine receptor
DN	dysplastic nevus
ECM	extracellular matrix
EGFR	epidermal growth factor receptor
EMT	epithelial-mesenchymal transition
EV	epidermodysplasia verruciformis
FA	Fanconi anaemia
FLT3	FMS-like tyrosine kinase 3
FSD	Ferguson-Smith disease
GARP	glycoprotein A repetitions predominant
GATA2	GATA binding protein 2
GOF	gain-of-function
GTP	guanosine triphosphate
GVHR	graft-versus host reaction
HER2	human epidermal growth factor receptor 2
HIES	hyper-IgE recurrent infection syndrome
HIV	human immunodeficiency virus
HPV	human papilloma virus
ICI	immune checkpoint inhibitor
interleukin	IL
irAE	immune-related adverse event
KA	keratoacanthoma
KC	keratinocyte
LC	Langerhans cell
LOF	Loss-of-function
MAPK	mitogen-activated protein kinase
MEK1	MAP2K1
MEK2	MAP2K2
MN	melanocytic nevus
MonoMAC	monocytopenia and mycobacterial infection
NOTCH1	notch receptor 1
OCA	oculocutaneous albinism
OR	objective responses
PD-1	programmed death-1
PD-1Ab	anti-PD-1 antibody
PD-L1	programmed death-ligand 1
PID	primary immunodeficiency
PMN	polymorphonuclear neutrophil
PTEN	phosphatase and tensin homolog
PY	people/year
R	receptor
RDEB	recessive dystrophic epidermolysis bullosa
RTKI	receptor tyrosine kinase inhibitors
SC	stratum corneum
SCID	severe combined immune deficiency
SEER	Surveillance, Epidemiology, and End Results
SHH	Sonic Hedgehog
SOX10	sex determining region Y-box 10
ST	signal transducer
STAT	signal transducer and activator of transcription
TERT	telomerase reverse transcriptase
TGF-b	transforming growth factor beta
Th	T helper
TMB	tumour mutational burden
TP53	tumour protein 53
TYK2	tyrosine kinase 2
UICC	Union for International Cancer Control
UV	ultraviolet
UVR	UV radiation
WHIM	Warts, Hypogammaglobulinemia, Infections, Myelocathexis