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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Pain. 2020 Oct;161(10):2344–2352. doi: 10.1097/j.pain.0000000000001921

Figure 3.

Figure 3.

Cisplatin treatment promotes neuronal hyperactivity by multiple electrophysiological alterations. Data were collected from DRG neurons isolated 10 days after the first injection of PBS or cisplatin. Recombinant IL-10 (10 ng/ml or 0.5 nM) was added 15–30 min before recording. A. Resting membrane potential (RMP, mV). PBS vs. cisplatin: one-way ANOVA followed by Sidak’s multiple correction test p=0.038. B. Action potential (AP) voltage threshold (mV): one-way ANOVA followed by Sidak’s multiple correction test p=0.0022, PBS vs. cisplatin: p=0.025. C. Rheobase (pA) Kruskal-Wallis test with Dunn’s correction for multiple comparisons p=0.0003; PBS vs. cisplatin: p=0.0005. Data are shown as mean ± SEM.