Table 4.
Pathway enrichment in the group of patients at low risk of hypoxia in the Gene Expression Omnibus database.
| NAME | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val |
|---|---|---|---|---|---|---|
| OXIDATIVE_PHOSPHORYLATION | 180 | -0.5181038 | -1.8664485 | 0.017612524 | 0.052985493 | 0.035 |
| FATTY_ACID_METABOLISM | 153 | -0.5680401 | -1.8461372 | 0.00203666 | 0.03559099 | 0.046 |
| PEROXISOME | 101 | -0.53683174 | -1.8330911 | 0 | 0.029562779 | 0.051 |
| CHOLESTEROL_HOMEOSTASIS | 71 | -0.54806143 | -1.6309602 | 0.021276595 | 0.15649396 | 0.239 |
| ADIPOGENESIS | 189 | -0.41682148 | -1.5094645 | 0.035433073 | 0.32561186 | 0.449 |
| XENOBIOTIC_METABOLISM | 193 | -0.52328324 | -1.5083747 | 0.028985508 | 0.2722546 | 0.449 |
| REACTIVE_OXYGEN_SPECIES_PATHWAY | 47 | -0.4019267 | -1.376308 | 0.11977186 | 0.51835406 | 0.644 |
| GLYCOLYSIS | 194 | -0.39022183 | -1.3331028 | 0.12045889 | 0.56736577 | 0.716 |
| P53_PATHWAY | 188 | -0.3891394 | -1.2930824 | 0.124756336 | 0.61373806 | 0.757 |
| BILE_ACID_METABOLISM | 109 | -0.45229995 | -1.2606792 | 0.17364016 | 0.63521326 | 0.791 |
| ESTROGEN_RESPONSE_LATE | 197 | -0.3940817 | -1.2011873 | 0.156 | 0.73189086 | 0.858 |
| UV_RESPONSE_UP | 153 | -0.34357396 | -1.175342 | 0.19662921 | 0.73222524 | 0.88 |
| MYC_TARGETS_V2 | 56 | -0.4696598 | -1.1727189 | 0.37304688 | 0.6814103 | 0.88 |
| MTORC1_SIGNALING | 189 | -0.38030684 | -1.1696959 | 0.29032257 | 0.6386857 | 0.882 |
| PI3K_AKT_MTOR_SIGNALING | 103 | -0.29268706 | -1.132223 | 0.27868852 | 0.6835487 | 0.904 |
| ESTROGEN_RESPONSE_EARLY | 193 | -0.32482004 | -1.0662084 | 0.33464566 | 0.79412293 | 0.936 |
| PANCREAS_BETA_CELLS | 40 | -0.42545584 | -1.057426 | 0.38690478 | 0.767329 | 0.94 |
| HEME_METABOLISM | 189 | -0.2667636 | -1.0508605 | 0.36575875 | 0.7411266 | 0.942 |
| DNA_REPAIR | 144 | -0.298164 | -1.0362988 | 0.42330098 | 0.73253185 | 0.943 |
| APOPTOSIS | 159 | -0.3165646 | -0.9227984 | 0.57114625 | 0.955858 | 0.981 |
| SPERMATOGENESIS | 132 | -0.24104334 | -0.86871046 | 0.6871287 | 1 | 0.988 |
| COMPLEMENT | 194 | -0.32908297 | -0.8492691 | 0.6442308 | 1 | 0.991 |
| APICAL_JUNCTION | 188 | -0.27416155 | -0.83836824 | 0.64705884 | 1 | 0.992 |
| MYC_TARGETS_V1 | 185 | -0.271399 | -0.80545324 | 0.628 | 1 | 0.995 |
| INTERFERON_GAMMA_RESPONSE | 194 | -0.3529506 | -0.7729238 | 0.6927593 | 1 | 0.996 |
| INTERFERON_ALPHA_RESPONSE | 92 | -0.36440378 | -0.7677859 | 0.6827853 | 1 | 0.996 |
| ALLOGRAFT_REJECTION | 193 | -0.32352465 | -0.7621619 | 0.69921875 | 1 | 0.996 |
| IL2_STAT5_SIGNALING | 193 | -0.24943894 | -0.74676377 | 0.8172888 | 1 | 0.997 |
| UNFOLDED_PROTEIN_RESPONSE | 103 | -0.20758167 | -0.70057595 | 0.7745665 | 1 | 0.998 |
| TNFA_SIGNALING_VIA_NFKB | 194 | -0.30261576 | -0.6995795 | 0.80670613 | 1 | 0.998 |
| HYPOXIA | 190 | -0.24055389 | -0.6963746 | 0.8644401 | 1 | 0.998 |
| MITOTIC_SPINDLE | 198 | -0.19739081 | -0.6422138 | 0.87279844 | 1 | 0.999 |
| NOTCH_SIGNALING | 31 | -0.2139055 | -0.6397593 | 0.9166667 | 1 | 0.999 |
| E2F_TARGETS | 190 | -0.2648517 | -0.622124 | 0.78019804 | 1 | 0.999 |
| INFLAMMATORY_RESPONSE | 198 | -0.25689715 | -0.6020838 | 0.9265873 | 0.99692255 | 0.999 |
| IL6_JAK_STAT3_SIGNALING | 87 | -0.23669887 | -0.56183934 | 0.9643564 | 0.99789304 | 1 |
| PROTEIN_SECRETION | 95 | -0.16205812 | -0.5151241 | 0.97137016 | 0.9930653 | 1 |
| G2M_CHECKPOINT | 185 | -0.19927993 | -0.5018363 | 0.89065605 | 0.9723166 | 1 |