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. 2021 Mar 8;22(5):2717. doi: 10.3390/ijms22052717

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The overall bias for the studies regarding the lung utilizing mouse models was a high risk of bias (56.4%) and some concerns (43.6%). The selection of the reported result had a high risk of bias (46.8%) and some concerns (53.2%). The measurement of the outcome had a high risk of bias (12.8%), some concerns (32.7%), and low risk of bias (54.5%). The missing outcome data domain had a low risk of bias (99.4%) and a high risk of bias (0.6%). Deviations from intended interventions had a low risk of bias (91%), some concerns (3.8%), and high risk of bias (4.5%). The randomization process had a high risk of bias (14.1%), some concerns (80.1%), and low risk of bias (5.8%).