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. 2021 Mar 8;22(5):2717. doi: 10.3390/ijms22052717

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The overall bias for all the studies regarding the liver was a high risk of bias (50%) and some concerns (50%). The selection of the reported result had a high risk of bias (39.3%) and some concerns (60.7%). The measurement of the outcome had a low risk of bias (60.7%), some concerns (28.6%), and high risk of bias (10.7%). The missing outcome data and the deviations from intended interventions domain had a low risk of bias of 100%. The randomization process had a high risk of bias (14.3%), some concerns (78.6%), and low risk of bias (7.1%).