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. 2021 Mar 8;22(5):2716. doi: 10.3390/ijms22052716

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic depiction of the elastic microbril, containing perlecan and fibrillin as functional omponents. (a) Schematic depiction of an elastic microfibril and its components. Electron micrographs of tannic acid-glutaraldehyde-fixed samples demonstrating the central amorphous elastin (E) within a microfibril in (b) longitudinal (magnification ×18,000) and (c) cross-section (magnification ×85,000); (d) Rotary shadowing images showing the characteristic interrupted globular domains in type VI collagen. Segment b, c reproduced from [55]. Segment d [56] under Open Access. Arrows in (b). depict microfibrillar material, E amorphous elastin. Arrowheads in (c). depict microfibrils in cross section, whilst arrows indicate collagen fibres in cross section.