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. 2021 Mar 8;22(5):2716. doi: 10.3390/ijms22052716

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Perlecan and elastin are components of a basal lamina in the knee joint endothelium. (a) Haematoxylin & eosin stained tissue section of an 18 month old ovine knee synovium specimen. Confocal localisation of perlecan (b, red), elastin (c, green), DAPI-stained cell nuclei (d) and merged image showing colocalisation of perlecan and elastin (e, yellow) within an elastic lamina and surrounding a synovial blood vessel. The arrows indicate the surface of the synovium.The asterisk indicates a blood vessel in the synovium. Figure reproduced from [54] with permission.