Table 1.
Patient and tumor characteristics by tumor type.
| Parameter | Total (N = 333) | Non-NPC (N = 189) | NPC (N = 144) |
|---|---|---|---|
| Age (N = 314) | |||
| Median (min, max) | 60.2 (14.3, 88.3) | 64.9 (37.1, 88.3) | 51.6 (14.3, 81.5) |
| N (%) | N (%) | N (%) | |
| Sex (N = 333) | |||
| Female | 52 (15.6) | 16 (8.5) | 36 (24.8) |
| Male | 282 (84.4) | 173 (91.5) | 109 (75.2) |
| Alcohol Abuse (N = 292) | |||
| No | 145 (49.7) | 47 (26.6) | 98 (85.2) |
| Yes | 147 (50.3) | 130 (73.4) | 17 (14.8) |
| Smoking (N = 293) | |||
| No | 60 (20.5) | 19 (10.8) | 41 (35.0) |
| Yes | 233 (79.5) | 157 (89.2) | 76 (65.0) |
| Histological Type (N = 307) | |||
| Non-Keratinizing Carcinoma | 37 (12.1) | 0 (0.0) | 37 (28.7) |
| Squamous Cell Carcinoma | 189 (61.6) | 172 (96.6) | 17 (13.2) |
| Undifferentiated Carcinoma | 77 (25.1) | 2 (1.1) | 75 (58.1) |
| Other | 4 (1.3) | 4 (2.2) | 0 (0.0) |
| Primary Tumor Location (N = 318) | |||
| Hypopharynx | 1 (0.3) | 1 (0.57) | 0 (0.0) |
| Larynx | 149 (46.9) | 149 (85.6) | 0 (0.0) |
| Major Salivary Glands | 2 (0.6) | 2 (1.1) | 0 (0.0) |
| Nasopharynx | 144 (45.3) | 0 (0.0) | 144 (100.0) |
| Oral Cavity | 11 (3.5) | 11 (6.3) | 0 (0.0) |
| Oropharynx | 7 (2.2) | 7 (4.0) | 0 (0.0) |
| Paranasal Sinuses | 4 (1.3) | 4 (2.3) | 0 (0.0) |
| T (N = 272) | |||
| T1 | 45 (16.5) | 19 (11.3) | 26 (25.0) |
| T2 | 79 (29.0) | 34 (20.2) | 45 (43.3) |
| T3 | 94 (34.6) | 77 (45.8) | 17 (16.3) |
| T4 | 54 (19.9) | 38 (22.6) | 16 (15.4) |
| N (N = 275) | |||
| N0 | 126 (45.8) | 114 (67.1) | 12 (11.4) |
| N1 | 42 (15.3) | 14 (8.2) | 28 (26.7) |
| N2 | 80 (29.1) | 33 (19.4) | 47 (44.8) |
| N3 | 23 (8.4) | 5 (2.9) | 18 (17.1) |
| Nx | 4 (1.5) | 4 (2.4) | 0 (0.0) |
| Stage (N = 281) | |||
| I | 19 (6.8) | 15 (9.0) | 4 (3.5) |
| II | 52 (18.5) | 23 (13.8) | 29 (25.4) |
| III | 105 (37.4) | 61 (36.5) | 44 (38.6) |
| IV | 105 (37.4) | 68 (40.7) | 37 (32.5) |
| Surgery (N = 176) | |||
| No | 33 (18.8) | 33 (18.8) | - |
| Yes | 143 (81.3) | 143 (81.3) | - |
| Type of Surgery (N = 142) | |||
| Chordectomy | 8 (5.6) | 8 (5.6) | - |
| Hemiglossectomy | 5 (3.5) | 5 (3.5) | - |
| Hemiglossectomy and Laryngectomy | 2 (1.4) | 2 (1.4) | - |
| Laryngectomy | 113 (79.6) | 113 (79.6) | - |
| Other | 14 (9.9) | 14 (9.9) | - |
| Treatment Received (N = 311) | |||
| No | 44 (14.1) | 43 (23.9) | 1 (0.8) |
| Yes | 267 (85.9) | 137 (76.1) | 130 (99.2) |
| Type of First Treatment Received (N = 267) | |||
| Induction Chemotherapy | 10 (3.8) | 0 (0.0) | 10 (7.7) |
| Primary concomitant CT and RT | 179 (67.0) | 65 (47.4) | 114 (87.7) |
| Primary RT | 34 (12.7) | 33 (24.1) | 1 (0.8) |
| RT after First Progression | 1 (0.4) | 1 (0.7) | 0 (0.0) |
| Adjuvant | 32 (12.0) | 29 (21.2) | 3 (2.3) |
| First-Line | 11 (4.1) | 9 (6.6) | 2 (1.5) |
The percentages for the type of surgery and the type of primary treatment were calculated from the total number of patients with available data that had undergone surgery and had received treatment, respectively.