Table 2.
Frequency distribution of the examined variants in the total cohort and by tumor type.
| Parameter | Total (N = 293) | Non-NPC (N = 149) | NPC (N = 144) |
|---|---|---|---|
| VEGFA rs699947 (−2578) (N = 286) | |||
| A | 40 (14.0) | 20 (13.4) | 20 (14.6) |
| AC | 136 (47.6) | 73 (49.0) | 63 (46.0) |
| C | 110 (38.5) | 56 (37.6) | 54 (39.4) |
| VEGFA rs12664104 (N = 285) | |||
| G | 285 (100.0) | 149 (100.0) | 136 (100.0) |
| VEGFA rs34376996 (N = 258) | |||
| T | 258 (100.0) | 149 (100.0) | 109 (100.0) |
| VEGFA rs144854329 (N = 289) | |||
| het del18bp | 148 (51.2) | 73 (49.0) | 75 (53.6) |
| hom del18bp | 101 (34.9) | 56 (37.6) | 45 (32.1) |
| reference | 40 (13.8) | 20 (13.4) | 20 (14.3) |
| VEGFA rs35864111 (N = 289) | |||
| het ins1bp | 148 (51.2) | 73 (49.0) | 75 (53.6) |
| hom ins1bp | 101 (34.9) | 56 (37.6) | 45 (32.1) |
| reference | 40 (13.8) | 20 (13.4) | 20 (14.3) |
| VEGFA rs833061 (-1498) (N = 272) | |||
| C | 55 (20.2) | 31 (20.8) | 24 (19.5) |
| CT | 135 (49.6) | 75 (50.3) | 60 (48.8) |
| T | 82 (30.1) | 43 (28.9) | 39 (31.7) |
| VEGFA rs149983590 (N = 288) | |||
| C | 287 (99.7) | 149 (100.0) | 138 (99.3) |
| CA | 1 (0.35) | 0 (0.0) | 1 (0.72) |
| VEGFA rs833062 (N = 276) | |||
| CT | 8 (2.9) | 7 (4.7) | 1 (0.79) |
| T | 268 (97.1) | 142 (95.3) | 126 (99.2) |
| VEGFA rs1570360 (−1154) (N = 289) | |||
| A | 91 (31.5) | 60 (40.3) | 31 (22.1) |
| G | 97 (33.6) | 36 (24.2) | 61 (43.6) |
| GA | 101 (34.9) | 53 (35.6) | 48 (34.3) |
| VEGFA rs28357093 (N = 289) | |||
| A | 289 (100.0) | 149 (100.0) | 140 (100.0) |
| VEGFA rs13207351 (−1190) (N = 289) |
|||
| A | 136 (47.1) | 69 (46.3) | 67 (47.9) |
| AG | 64 (22.1) | 34 (22.8) | 30 (21.4) |
| G | 89 (30.8) | 46 (30.9) | 43 (30.7) |
| VEGFA rs79469752 (N = 289) | |||
| C | 289 (100.0) | 149 (100.0) | 140 (100.0) |
| VEGFA rs59260042 (N = 289) | |||
| C | 289 (100.0) | 149 (100.0) | 140 (100.0) |
| VEGFA rs3025039 (+936) (N = 285) | |||
| C | 200 (70.2) | 104 (70.3) | 96 (70.1) |
| CT | 71 (24.9) | 34 (23.0) | 37 (27.0) |
| T | 14 (4.9) | 10 (6.8) | 4 (2.9) |
| VEGFA rs149179279 (N = 285) | |||
| C | 285 (100.0) | 148 (100.0) | 137 (100.0) |
| VEGFA rs112256643 (N = 285) | |||
| C | 285 (100.0) | 148 (100.0) | 137 (100.0) |
| VEGFA rs112005313 (N = 285) | |||
| G | 285 (100.0) | 148 (100.0) | 137 (100.0) |
| VEGFA rs187429037 (N = 283) | |||
| A | 283 (100.0) | 148 (100.0) | 135 (100.0) |
| VEGFA rs111933757 (N = 280) | |||
| T | 280 (100.0) | 148 (100.0) | 132 (100.0) |
| EDNRA rs5333 (p.H323H) (N = 289) | |||
| C | 13 (4.5) | 6 (4.1) | 7 (5.0) |
| CT | 114 (39.4) | 58 (39.2) | 56 (39.7) |
| T | 162 (56.1) | 84 (56.8) | 78 (55.3) |
| EDNRA rs5334 (p.E335E) (N = 287) | |||
| A | 12 (4.2) | 6 (4.1) | 6 (4.3) |
| AG | 113 (39.4) | 58 (39.2) | 55 (39.6) |
| G | 162 (56.4) | 84 (56.8) | 78 (56.1) |
| EDNRA rs10305924 (N = 285) | |||
| AG | 1 (0.35) | 0 (0.0) | 1 (0.73) |
| G | 284 (99.6) | 148 (100.0) | 136 (99.3) |
| EDNRA rs17856670 (p.L322V) (N = 289) | |||
| C | 289 (100.0) | 148 (100.0) | 141 (100.0) |
| EDNRA rs112710542 (N = 288) | |||
| AG | 6 (2.1) | 0 (0.0) | 6 (4.3) |
| G | 282 (97.9) | 147 (100.0) | 135 (95.7) |
| FAS rs1800682 (-670) (N = 290) | |||
| A | 74 (25.5) | 40 (26.8) | 34 (24.1) |
| AG | 165 (56.9) | 75 (50.3) | 90 (63.8) |
| G | 51 (17.6) | 34 (22.8) | 17 (12.1) |
| FAS rs34995925 (N = 290) | |||
| T | 290 (100.0) | 149 (100.0) | 141 (100.0) |
| FAS rs2234768 (−690) (N = 290) | |||
| C | 1 (0.34) | 1 (0.67) | 0 (0.0) |
| CT | 52 (17.9) | 27 (18.1) | 25 (17.7) |
| T | 237 (81.7) | 121 (81.2) | 116 (82.3) |
| FAS rs150130637 (N = 286) | |||
| A | 286 (100.0) | 149 (100.0) | 137 (100.0) |
| NBS1 rs1805794 (p.E185Q) (N = 291) | |||
| C | 37 (12.7) | 21 (14.1) | 16 (11.3) |
| G | 109 (37.5) | 61 (40.9) | 48 (33.8) |
| GC | 145 (49.8) | 67 (45.0) | 78 (54.9) |
| NBS1 rs192240705 (N = 291) | |||
| T | 291 (100.0) | 149 (100.0) | 142 (100.0) |
| NBS1 rs780661058 (p.A183A) (N = 291) | |||
| A | 291 (100.0) | 149 (100.0) | 142 (100.0) |
| NBS1 rs151070415 (p.A183T) (N = 291) | |||
| G | 291 (100.0) | 149 (100.0) | 142 (100.0) |
| NBS1 rs61754966 (p.I171V) (N = 291) | |||
| A | 289 (99.3) | 148 (99.3) | 141 (99.3) |
| AG | 2 (0.7) | 1 (0.7) | 1 (0.7) |
| NBS1 rs182756889 (p.R169C) (N = 291) | |||
| C | 291 (100.0) | 149 (100.0) | 142 (100.0) |