Table 1D.
Clinical and laboratory features of patients who died (n = 5).
| Parameters | COVID group (n = 2) |
Non-COVID group (n = 3) |
|||
|---|---|---|---|---|---|
| Cases | Case 1 | Case 2 | Case 1 | Case 2 | Case3 |
| Age, yrs | 19 | 31 | 24 | 47 | 24 |
| Sex | M | M | F | M | F |
| Clinical features | ACS, splenectomy, asthma | ACS, previous DVT, splenectomy, asthma | Mild VOC | ACS, AVN hips, cholecystectomy, splenectomy | ACS, cholecystectomy, |
| Presenting feature | Headache, back pain | Back and chest pain | Fever, pain, vomiting, tachypnea, reduced saturation | Back pain, fever, cough reduced saturation | Fever, tachycardia, tachypnea, |
| Terminal event | Cerebral haemorrhage | COVID pneumonia, left occipital lobe infarction, ACS, renal failure | Overwhelming sepsis | Fat embolism syndrome, septicaemia | Gram-negative septicaemia with multi-organ failure |
| Hb baseline, g/dl, | 8.5 | 10.3 | 7.8 | 9.8 | 9.6 |
| Hb at presentation, g/dl, | 9.9 | 8.2 | 4.4 | 6.9 | 7.2 |
| WBC baseline, X109/L, | 12.6 | 12.3 | 10.6 | 11.6 | |
| WBC at presentation, X109/L, | 14.2 | 54.2 | 42.9 | 6.7 | 34.5 |
| Platelets baseline, X109/L, | 461 | 331 | 268 | 132 | |
| Platelets at presentation, X109/L, | 92 | 108 | 137 | 15 | 15 |
| Lymphocytes, X109/L, | 5.9 | 2.8 | 3.1 | 1.8 | 4.4 |
| LDH at presentation, u/L | 737 | 10024 | 1987 | 6762 | |
| S. ferritin, ng/ml, | 1180 | 392300 | 61781 | 76808 | |
| CRP, mg/L | 41 | 449 | 442 | 405 | 449 |
| Hb F, % | 7.4 | 2.6 | 36.3 | 10.1 | 12.3 |
| Hb A2, % | 5.1 | 4.4 | 3.9 | 6.6 | 5.3 |
Key: ACS- Acute Chest Syndrome; AVN- Avascular Necrosis; DVT- Deep Vein Thrombosis; LDH – Lactic Dehydrogenase; CRP-C-Reactive Protein.