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. 2021 Mar 16;28(6):661–674. doi: 10.3727/096504020X16014648664459

Table 2.

Tumor-Suppressing Roles of Fzds

Fzds Wnt Pathways Malignant Tumors Functions References
Fzd1 Noncanonical FTC Growth, invasion, migration 83
Fzd2 Noncanonical HCC Growth, stemness 85
Fzd6 Noncanonical Gastric, prostate, breast cancers Growth, migration, stemness 87, 88
Fzd5 Noncanonical Prostate cancer Growth 90, 91
Fzd8 Noncanonical Pancreatic cancer, glioma Stemness, growth 92, 93
Fzd9 Noncanonical NSCLC EMT 99, 100