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ΔTm of analyzed sequences in the presence of 5a, 5e, 5g, and 5h. 1 ΔTm values are the differences in the melting temperatures of DNA in the presence and absence of ligands. The error on ΔTm is ±0.5 °C.
| Ligand |
KRAS 22RT ΔTm (°C) 1 |
BCL2-G4 ΔTm (°C) 1 |
Tel 23 Δ Tm (°C) 1 |
Hairpin Duplex Δ Tm (°C) 1 |
|---|---|---|---|---|
| 5a | +7.0 | −3.0 | −3.2 | +1.0 |
| 5e | 0 | 0 | 0 | +5.4 |
| 5g | 0 | 0 | −2.0 | 0 |
| 5h | 0 | +1.0 | +1.0 | +3.3 |
