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. 2021 Mar 8;22(5):2731. doi: 10.3390/ijms22052731
PCa Prostate Cancer
PSMA-D4 Prostate-Specific Membrane Antigen ligand conjugated with DOTA (Glu-CO-Lys-L-Trp-4-Amc-DOTA)
DOTA 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tetraxetan
mCRPC metastatic castration-resistant prostate cancer
PSA prostate-specific antigen
GCPII glutamate carboxypeptidase II
BFC bifunctional chelator
LNCaP Lymph Node Carcinoma of the Prostate
COMU 1-[(1-(cyano-2-ethoxy-2-oxoethylideneaminooxy)dimethylaminemorpholino)]uronium hexafluorophosphate
KD binging affinity
Bmax maximum receptor density
CLI Cerenkov luminescence imaging
ROI region of interest
SA specific activity
RCY radiochemical yield
ATCC American Type Culture Collection
FBS fetal bovine serum
ID injected dose
SD standard deviation
SE electrospray soure
IT ion trap
TOF time of flight analyzer
TCD Thermal conductivity detector