Table 1.
OVERALL POPULATION (N = 6095) |
YEAR 2019 (N = 3389) |
YEAR 2020 (N = 2706) |
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---|---|---|---|---|---|---|---|---|---|
RASI (n = 2441) | No RASI 2019 (n = 3654) | P value | RASI (n = 1375) | No RASI 2019 (n = 2014) | P value | RASI (n = 1066) | No RASI 2020 (n = 1640) | P value | |
Age (median, IQR) | 67 [58–75] | 62 [53–71] | < 0.001 | 67 [58–75] | 62 [53–71] | < 0.001 | 67 [59–75] | 62 [53–71] | < 0.001 |
Age > 75 year – n. (%) | 664 (27.2) | 633 (17.6) | < 0.001 | 373 (27.1) | 358 (17.8) | < 0.001 | 291 (27.3) | 275 (16.8) | < 0.001 |
Male gender – n. (%) | 1801 (71.3) | 2870 (75.8) | < 0.001 | 969 (70.5) | 1527 (75.8) | 0.001 | 765 (71.8) | 1256 (76.6) | 0.005 |
Diabetes Mellitus- n (%) | 758 (31.1) | 568 (15.5) | < 0.001 | 428 (31.1) | 316 (15.7) | < 0.001 | 330 (31) | 252 (15.4) | < 0.001 |
Hypertension- n (%) | 2170 (88.9) | 1148 (31.4) | < 0.001 | 1234 (89.7) | 634 (31.5) | < 0.001 | 936 (87.8) | 514 (31.3) | < 0.001 |
Hypercholesterolemia - n (%) | 1225 (50.2) | 1350 (36.9) | < 0.001 | 679 (49.4) | 739 (36.7) | < 0.001 | 546 (51.2) | 611 (37.3) | < 0.001 |
Active Smokers – n (%) | 895 (36.7) | 1639 (44.9) | < 0.001 | 514 (37.4) | 901 (44.7) | < 0.001 | 381 (35.7) | 738 [45] | < 0.001 |
Family History of CAD - n (%) | 550 (22.5) | 859 (23.5) | 0.37 | 319 (23.2) | 479 (23.8) | 0.71 | 231 (21.7) | 380 (23.2) | 0.37 |
Previous STEMI- n (%) | 396 (16.2%) | 184 (5.0) | < 0.001 | 219 (15.9) | 101 (5) | < 0.001 | 177 (16.6) | 83 (5.1) | < 0.001 |
Previous PCI – n (%) | 500 (20.5) | 269 (7.4) | < 0.001 | 276 (20.1) | 154 (7.6) | < 0.001 | 224 (21) | 115 (7) | < 0.001 |
Previous CABG - n (%) | 67 (2.7) | 40 (1.1) | < 0.001 | 30 (2.2) | 27 (1.3) | 0.08 | 37 (3.5) | 13 (0.8) | < 0.001 |
Referral to Primary PCI Hospital | |||||||||
Ambulance (from community) – n (%) | 1304 (53.4) | 2057 (56.3) | 0.027 | 717 (52.1) | 1091 (54.2) | 0.25 | 587 (55.1) | 966 (58.9) | 0.049 |
Time delays | |||||||||
Ischemia time, median [25–75th] | 200 [130–358] | 184 [120–310] | < 0.001 | 200 [1125–330] | 180 [120–300] | 0.009 | 210 [135–385] | 195 [125–330] | 0.006 |
Total Ischemia time > 12 h – n (%) | 270 (11.1) | 348 (9.5) | 0.051 | 123 (8.9) | 184 (9.1) | 0.85 | 147 (13.8) | 164 (10.0) | 0.003 |
Door-to-balloon time, median [25–75th] | 40 [25–60] | 35 [22–60] | < 0.001 | 38 [25–60] | 32 [21–60] | 0.006 | 40 [28–63] | 35 [24–60] | < 0.001 |
Door-to-balloon time > 30 min (%)– n (%) | 1490 (61.1) | 1936 [53] | < 0.001 | 800 (58.2) | 1038 (51.6) | < 0.001 | 690 (64.8) | 898 (54.8) | < 0.001 |
Clinical Presentation | |||||||||
Anterior STEMI – n (%) | 1079 (44.2) | 1695 (46.4) | 0.093 | 607 (44.1) | 941 (46.7) | 0.14 | 472(44.3) | 754 [46] | 0.41 |
Out-of-hospital cardiac arrest – n (%) | 134 (5.5) | 280 (7.7) | 0.001 | 77 (5.6) | 148 (7.3) | 0.045 | 57 (5.3) | 132 (8) | 0.007 |
Cardiogenic shock– n (%) | 198 (8.1) | 314 (8.6) | 0.51 | 118 (8.6) | 147 (7.3) | 0.17 | 80 (7.5) | 167 (10.2) | 0.02 |
Rescue PCI for failed thrombolysis – n (%) | 93 (3.8) | 126 (3.4) | 0.46 | 51 (3.7) | 73 (3.6) | 0.93 | 42 (3.9) | 53 (3.2) | 0.34 |
*Mann-Whitney test
CAD = Coronary Artery Disease; STEMI = ST-segment Elevation Myocardial Infarction; PCI = Percutaneous Coronary Intervention; CABG 0 Coronary Artery Bypass Graft;