Table 2. Effect of PR on COPD/respiratory, sleep and neurocognitive variables.

Variables		Pre-PR	Post-PR	Mean change (95% CI)	Significance (p-value)
St. George’s Respiratory Questionnaire (SGQR), n = 64
	SGQR score, mean ± SD	60.9 ± 16.3	53.2 ± 16.4	7.7 (5.2 to 10.2)	<0.0001*
	SGQR score, median (IQR)	61.1 (48.8 to 72.52)	56.7 (40.9 to 64.8)
Pulmonary Functional Status & Dyspnea Questionnaire
“Indicate how you have felt most days during past year?”, n = 53
	VAS, mean ± SD	5.6 ± 1.6	5.3 ± 1.7	0.3 (-0.1 to 0.7)	0.15*
	VAS score, median (IQR)	6 (5 to 7)	5 (4.2 to 6.2)
“Indicate how you feel today?”, n = 60
	VAS, mean ± SD	4.9 ± 2.2	4.0 ± 2.1	0.8 (0.2 to 1.5)	0.01*
	VAS Score, median (IQR)	5 (4 to 6)	4 (2 to 5.5)
“Indicate how you feel with most day-to-day activities?”, n = 60
	VAS, mean ± SD	5.9 ± 2.0	5.0 ± 1.9	0.9 (0.4 to 1.4)	0.001*
	VAS Score, median (IQR)	6 (5 to 7)	5 (4 to 6)
COPD Assessment Test, n = 46
	CAT score, mean ± SD	24.2 ± 7.0	17.5 ± 6.2	4.5 (2.5 to 6.5)	<0.0001**
	CAT score, median (IQR)	25 (20.5 to 29.5)	21 (16 to 24)
mMRC dyspnea scale, n = 63
	mMRC score, mean ± SD	2.4 ± 1.1	1.6 ± 0.9	0.76 (0.4 to 1.0)	<0.0001**
	mMRC score, median (IQR)	2 (2–4)	2 (1–2)
SLUMS score, n = 64
	SLUMS score, mean ± SD	24.5 ± 3.2	25.7 ± 2.8	1.2 (0.4 to 2.0)	0.010*
	SLUMS score, median (IQR)	25 (23 to 27)	26 (24 to 27)
Geriatric Depression Scale, n = 66
	GDS score, mean ± SD	12.7 ± 7.6	11.6 ± 7.7	1.1 (-0.1 to 2.3)	0.051*
	GDS score, median (IQR)	13.5 (6 to 18)	11 (5 to 16)
6-min Walk test, n = 66
	6-MWD, meters, mean ± SD	340 ± 114	394 ± 129	54 (34 to 74)	<0.0001*
	6-MWD, meters, median (IQR)	373 (300.3 to 431.9)	407.3 (331.6 to 165.7)
Epworth Sleepiness Scale, n = 61
	ESS score, mean ± SD	7.7 ± 5.1	8.0 ± 4.5	-0.3 (-1.4 to 0.7)	0.54**
	ESS score, median (IQR)	8 (4 to 11)	8 (5 to 11)

Abbreviations: 95% CI (95% Confidence Interval); Statistics:

*Wilcoxson Signed rank test

**paired t-test.