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. 2021 Mar 2;12:627384. doi: 10.3389/fgene.2021.627384

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Copyright © 2021 Ran, Huang, Hu, Hu, Hu, Li, He, Liu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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KEGG enrichment analysis. The 13 pathways significantly enriched by DEGs (A) and the top 10 pathways with the most significant enrichment of lncRNA cis-target (B) and trans-target (C) genes. Point color represents the significance of enrichment, and point size represents the number of differentially expressed genes enriched in each pathway. (D) The corresponding DE lncRNAs of the DEGs enriched in the phosphatidylinositol signaling system pathway. (E) The Venn diagram of the pathways enriched by DEGs and the target genes of DE LncRNAs.