Figure 4.

Association of systemic levels of trimethyllysine with incident cardiovascular events in the multicentre Swiss ACS Cohort. (A) Box–Whisker plots of trimethyllysine levels among acute coronary syndrome patients depicting the relation of trimethyllysine with (yes) and without (no) incident major adverse cardiac events and mortality in 1 year. (B) Kaplan–Meier plots illustrating 1-year major adverse cardiac events risk stratified by the tertiles of trimethyllysine levels. (C) Forest plots indicating the risks of incident major adverse cardiac events and mortality according to the tertiles of trimethyllysine levels in 1 year. Symbols represent hazard ratios and the 5–95% confidence interval is indicated by line length. Hazard ratios by Cox modelling using adjustments for age, sex, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, smoking, history of diabetes mellitus and hypertension, and indices of renal function (estimated glomerular filtration rate).