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. 2021 Mar 9;22(5):2752. doi: 10.3390/ijms22052752

Table 1.

The MIC value of conventional antibiotic and synergistic effect of TCA combined with an antibiotic.

Antibiotics ATCC 33591 DPS-1 DPS-3
MIC (μg/mL) Fold FICI MIC (μg/mL) Fold FICI MIC (μg/mL) Fold FICI
Ampicillin 62.5 2 1 31.3 4 0.75 62.5 4 0.75
Oxacillin 62.5 4 0.75 500 2 1 500 8 0.25
Gentamicin 3.9 4 0.75 125 4 0.37 250 4 0.5
Vancomycin 250 8 0.25 250 2 1 500 2 1
Amoxicillin 62.5 8 0.63 125 4 0.5 125 8 0.25
Ceftazidine 125 2 1 125 2 1 250 4 0.75
Amikacin 31.2 4 0.38 31.2 8 0.25 62.5 16 0.19
Cefoxitin 31.2 4 0.75 62.5 8 0.62 250 4 0.5

TCA, trans-cinnamaldehyde; MIC, minimal inhibitory concentration; Fold, Fold reduction of the MIC of antibiotics. FICI, The fractional inhibitory concentrations index.