Table 2.
Baseline characteristics according to tertiles of diastolic blood pressure.
| Characteristics | 1st Tertile (≤ 68 mmHg) (n=97) | 2nd Tertile (69–76 mmHg) (n=93) | 3rd Tertile (> 76 mmHg) (n=95) | p for trend |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, mean±SD, y | 63.5±8.1 | 63.7±7.8 | 62.1±7.3 | 0.204 |
| Male sex, No. (%) | 70 (72.2) | 81 (87.1) | 82 (86.3) | 0.011 |
| Inclusion criteria (may have more than one), No. (%) | ||||
| History of MI | 48 (49.5) | 44 (47.3) | 38 (40.0) | 0.189 |
| History of PCI | 55 (56.7) | 63 (67.7) | 58 (61.7) | 0.471 |
| History of CABG | 22 (22.7) | 28 (30.1) | 18 (19.1) | 0.579 |
| Cardiovascular risk factors, No. (%) | ||||
| Hypertension | 79 (81.4) | 78 (83.9) | 83 (87.4) | 0.262 |
| Diabetes | 40 (41.2) | 22 (23.7) | 20 (21.1) | 0.002 |
| Anthropometric and blood pressure, mean±SD | ||||
| Weight, kg | 88.8±14.6 | 90.5±15.1 | 93.7±12.9 | 0.019 |
| Body mass index, kg/m2* | 30.6±3.7 | 30.3±3.5 | 31.0±3.6 | 0.417 |
| Waist circumference, cm | 105.9±10.7 | 106.5±10.9 | 107.5±9.8 | 0.290 |
| Systolic BP, mmHg | 115.0±13.6 | 125.1±11.9 | 132.7±11.4 | <0.001 |
| Diastolic BP, mmHg | 63.3±4.4 | 72.3±2.2 | 83.6±6.1 | NA |
| Pulse pressure, mmHg | 51.8±12.9 | 52.9±12.0 | 49.1±9.7 | 0.122 |
| Complete blood count, mean±SD | ||||
| WBC, 109 cells/L | 6.8±1.8 | 6.8±2.8 | 6.4±1.6 | 0.240 |
| Monocytes, cells/μL | 532.6±175.7 | 511.4±145.6 | 534.5±169.5 | 0.941 |
| Neutrophils, cells/μL | 4291.6±1570.9 | 4249.0±1534.6 | 3994.8±1385.1 | 0.172 |
| Lymphocytes, cells/μL | 1722.4±619.9 | 1877.2±2157.3 | 1671.6±543.2 | 0.795 |
| Platelets, cells/μL | 192.8±50.2 | 187.5±52.0 | 197.3±50.9 | 0.547 |
| Lipids, mean±SD | ||||
| Total cholesterol, mg/dL a | 150.0±38.7 | 148.6±30.9 | 158.8±38.3 | 0.095 |
| Triglyceride, median [IQR], mg/dL b | 117.0 [79.0, 167.5] | 111.0 [77.0, 161.0] | 124.0 [83.0, 175.0] | 0.970 |
| HDL-C, mg/dL a | 46.2±14.1 | 47.8±15.0 | 47.3±13.9 | 0.617 |
| LDL-C, mg/dL a | 76.5±29.8 | 75.4±22.7 | 84.1±31.4 | 0.065 |
| Biochemical profile, mean±SD | ||||
| Glucose, mg/dL c | 112.4±38.2 | 106.4±39.9 | 102.7±23.6 | 0.052 |
| HbA1c, % (mmol/mol) | 6.3±1.1 | 6.1±1.0 | 6.1±.8 | 0.063 |
| Creatinine clearance (mL/min) | 99.0±31.4 | 102.2±27.1 | 102.6±22.5 | 0.363 |
| hs-CRP | 0.9 [0.4, 3.2] | 0.6 [0.4, 1.5] | 0.7 [0.3, 2.3] | 0.529 |
| Medication, No. (%) | ||||
| Statin | 95 (97.9) | 91 (97.8) | 86 (90.5) | 0.014 |
| Aspirin | 94 (96.9) | 85 (91.4) | 94 (98.9) | 0.493 |
| ACE-I | 56 (57.7) | 49 (52.7) | 52 (54.7) | 0.675 |
| ARB | 19 (19.6) | 16 (17.2) | 16 (16.8) | 0.620 |
| Hydrochlorothiazide | 19 (19.6) | 22 (23.7) | 15 (15.8) | 0.514 |
| Furosemide | 14 (14.4) | 7 (7.5) | 4 (4.2) | 0.012 |
| Calcium channel blocker | 22 (22.7) | 23 (24.7) | 23 (24.2) | 0.803 |
| Beta blockers | 78 (80.4) | 63 (67.7) | 65 (68.4) | 0.063 |
| On any antihypertensive medication, No. (%) | 96 (99.0) | 85 (91.4) | 86 (90.5) | 0.030 |
ACE-I = angiotensin converting enzyme inhibitor; ARB = angiotensin receptor blocker; BP = blood pressure; CABG = coronary artery bypass grafting; HbA1c = hemoglobin A1c; HDL-C = high density lipoprotein cholesterol; LDL-C = low density lipoprotein cholesterol; MI = myocardial infarction; PCI = percutaneous coronary intervention; WBC = white blood cell count.
a
To convert to SI unit (mmol/L), multiply by 0.0259
b
To convert to SI unit (mmol/L), multiply by 0.0113
c
To convert to SI unit (mmol/L), multiply by 0.0555