TABLE 2.

Competing Risk Regression for the Time to Development of Acute Kidney Injury

Variables	Univariate HR (95% CI)	p	Multivariate HR (95% CI)	p
Age	1.00 (0.99–1.02)	0.66	1.01 (0.99–1.03)	0.20
Female	0.14 (0.03–0.57)	0.006	0.13 (0.03–0.53)	0.005
Motorcycle or pedestrian accident	1.97 (1.22–3.16)	0.005	1.81 (1.12–2.92)	0.02
Injury Severity Score	1.01 (0.99–1.03)	0.51	1.01 (0.98–1.04)	0.50
International Mission for Prognosis and Analysis of Clinical Trials score	1.02 (1.01–1.03)	0.003	1.02 (1.00–1.03)	0.03
Acute Physiology And Chronic Health Evaluation II score	1.02 (0.99–1.05)	0.25	1.00 (0.96–1.03)	0.80
Any hypertonic saline day 1 or 2a	2.52 (1.59–4.00)	0.001	1.63 (0.94–2.84)	0.08
Any mannitol day 1 or 2a	3.52 (2.00–6.21)	< 0.001	2.27 (1.19–4.33)	0.01
Propensity to receive mannitol	1.04 (1.03–1.05)	< 0.0001	1.03 (1.01–1.04)	0.001

HR = hazard ratio.

^aInteraction between mannitol and hypertonic saline p = 0.81.