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. 2021 Jan 7;49(4):661–670. doi: 10.1097/CCM.0000000000004862

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Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine and Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 2. — Analysis of the microhemodynamics of the coronavirus disease 2019 (COVID-19) patients in comparison with those of the volunteers. COVID-19 patients had higher ratio capillary-to-systemic hematocrit (cHct/sHct) ratio (A) than in volunteers and higher functional capillary density (FCD) (B) than the volunteers. C, There was no evidence of plugged vessels in the COVID-19 patients as evidenced by a proportion of perfused vessel (PPV) > 94% in both groups. D, RBC velocity (RBCv) was significantly higher in COVID-19 patients than in the volunteers. E, Receiver-operating-characteristic curve analysis of the different microcirculatory hemodynamic parameters identifies cHct/sHct and RBCv as the parameters with the highest specificity and sensitivity for distinguishing the COVID-19 patients from the healthy volunteers. AUC = area under the curve.