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. 2021 Jan 7;49(4):661–670. doi: 10.1097/CCM.0000000000004862

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Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine and Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 3. — Microcirculatory leukocytes in coronavirus disease 2019 (COVID-19) patients. A, Examples of leukocytes present in the microcirculation are shown. B, Presence of leukocytes can be seen in a space time diagram as slanted white lines as they travel down the length of a capillary (y-axis) over time (x-axis). The number of such white lines per 4-s clip is used to calculate the number of leukocytes. The dark slanted lines measure the presence of the RBC lines. The slopes of these lines are used to calculate RBC velocities. C, The total number of leukocytes measured in capillary-postcapillary venule units shows that there are significantly more microcirculatory leukocytes in the COVID-19 patients than in the volunteers.