Table 2:
Comparison of brain MR imaging findings in patients with IVS4-type Fabry disease, with and without brain infarctions
| Infarction | Noninfarction | P Valuea | |
|---|---|---|---|
| No. | 9 | 17 | |
| Mean age (SD) (years) | 64.0 (5.2) | 56.8 (7.0) | .009 |
| Sex (M/F) | 6:3 | 14:3 | .332 |
| Area of infarction (anterior circulation/posterior circulation/both) | 3/2/4 | 0/0/0 | .012 |
| Hemorrhage/microbleeds | 0 (0%) | 0 (0%) | 1.000 |
| White matter scoresb | 2/4/2/1 | 13/4/0/0 | .023 |
| Pulvinar sign | 3 (33%) | 5 (29%) | .837 |
| Chiari I malformation | 0 (0%) | 0 (0%) | 1.000 |
| Vascular stenosisc | 2 (22%) | 0 (0%) | .041 |
| Mean diameter of BA (SD) (mm) | 2.57 (0.64) | 2.86 (0.61) | .301 |
| Laterality of BAb | 4/5/0/0 | 8/8/1/0 | .732 |
| Height of BA bifurcationb | 3/5/1 | 3/5/9 | .114 |
a
P, unadjusted.
b
Scale of 0/1/2/3.
c
Presence of focal stenosis of all intracranial arteries.