Table 4:
Brain MR imaging findings of male patients with IVS4 +919G>A and healthy controls
| Late-Onset Fabry Disease | Healthy Control | P Valuea | |
|---|---|---|---|
| No. | 20 | 20 | |
| Mean age (SD) (years) | 59.7 (7.5) | 58.5 (6.7) | .547 |
| Infarction | 6 (30%) | 0 (0%) | .010 |
| Area of infarction (anterior circulation/posterior circulation/both) | 1/1/4 | 0/0/0 | .070 |
| Hemorrhage/microbleeds | 0 (0%) | 0 (0%) | 1.000 |
| White matter scoresb | 13/5/1/1 | 14/5/1/0 | .792 |
| Pulvinar sign | 7 (35%) | 0 (0%) | .004 |
| Chiari I malformation | 0 (0%) | 0 (0%) | 1.000 |
| Vascular stenosisc | 1 (5%) | 2 (10%) | .513 |
| Mean diameter of BA (SD) (mm) | 2.91 (0.60) | 2.43 (0.72) | .041 |
| Laterality of BAb | 11/8/1/0 | 5/14/1/0 | .143 |
| Height of BA bifurcationb | 4/8/8 | 7/10/3 | .191 |
a
P, unadjusted.
b
Scale of 0/1/2/3.
c
Presence of focal stenosis of all intracranial arteries.