A, Illustration of the receiver operating characteristic curve of our algorithm for detecting volume-changing metastatic brain tumors at 1.5T, constructed from 233 different thresholding values of the Jacobian operator field (from 0 to −0.232, separated by −0.001). The arrow shows the optimal point of balance. B, Illustration of the ROC curve of our algorithm for detecting ΔMBTs at 3T, constructed from 656 different thresholding values of the Jacobian operator field (from 0 to −0.655, separated by −0.001). The arrow shows the optimal point of balance between sensitivity and specificity, which happens at the Jacobian value of −0.182.