Table 1:
Patient characteristics and temperature profilea
| Characteristics | |
|---|---|
| Mean age (yr) | 65 (range, 18–94) |
| NIHSS score | 18 (14–22) |
| Women | 60 (46.5%) |
| Presentation core infarction volumeb | 9.6 mL (1.5–25.3) |
| Hypoperfused volumec | 132.6 mL (84.2–204) |
| Occluded vessels | n (%) |
| Intracranial ICA | 17 (13.2%) |
| Extracranial ICA | 2 (1.6%) |
| M1 MCA | 63 (48.8%) |
| M2 MCA | 24 (18.6%) |
| ACA | 4 (3.1%) |
| Vertebrobasilar | 1 (0.8%) |
| Tandem | 18 (14%) |
| Reperfusion score | |
| mTICI 2b | 67 (52.9%) |
| mTICI 3 | 62 (48.1%) |
| Last known well to reperfusion | 414 min (295–572) |
| CTP to reperfusion | 119 min (84–162) |
| Procedure time to reperfusion | 58.0 min (38.5–94.5) |
| Total procedural duration | 77 min (51–118) |
| CTP-to-MRI time | 26.8 hr (20–47.2) |
| Last known well to MRI | 30.6 hr (24.0–51.2) |
| General anesthesia (No.) | 44 (34.1%) |
| Aspirin therapy (No.) | 125 (96.9%) |
| Received acetaminophen (No.) | 91 (70.5%) |
| Final infarct volume | 19.6 mL (8.3–45.2 mL) |
| Mean 90-day mRS | 2 |
| Favorable clinical outcome (mRS ≤2) (No.) | 77 (59.7%) |
| 90-day mortality (No.) | 11 (8.5%) |
| Population temperature minima (mean) | 35.3°C |
| Population temperature maxima (mean) | 37.9°C |
| Per-patient temperature fluctuation | 2.4°C (1.8°C–3.3°C) |
| Temperature increase from baseline | 1.6°C (1.0°C–2.5°C) |
Note:—ACA indicates anterior cerebral artery.
a
Data are reported as proportions and median (IQR), unless otherwise stated.
b
Relative cerebral blood flow <30% of contralateral normal tissues.
c
Tmax of >6 seconds.