Fig 2.

Representative segmentation images. Age is organized in columns increasing from left to right: 1 month, 5 months, 10 months, 1.2 years, 2.5 years, 7 years, and 15 years of age. Tissue types are arranged in upper-to-lower rows: GM, WM, CSF, and MY. The faint red line denotes the boundary of the intracranial mask. Note the suboptimal GM/WM segmentation in young children (upper 2 rows). At 0.1 year, there is complete assignment of WM as GM (upper left image); at 0.4 year, there is mislabeling with correct assignment of the internal capsule and centrum semiovale (not shown). At 0.8 year, some peripheral WM is assigned as GM. At 1.2 years, there is overall good segmentation with areas of mislabeling in the frontal and temporal lobes. By 2.5 years and beyond, GM and WM are correctly segmented. Note the assignment of parenchymal voxels as CSF in the youngest children (first column, third row).