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. 2016 Nov;37(11):2010–2018. doi: 10.3174/ajnr.A4867

Table 1:

Response criteria for primary central nervous system lymphoma

Response Brain Imaging Corticosteroid Dose Eye Examination Findings CSF Cytology Findings
CR No contrast enhancement None Normal Negative
CRu No contrast enhancement Any Normal Negative
Minimal abnormality Any Minor RPE abnormality Negative
PR 50% Decrease in enhancing tumor Irrelevant Minor RPE abnormality or normal Negative
No contrast enhancement Irrelevant Decrease in vitreous cells or retinal infiltrate Persistent or suspicious
PD 25% Increase in lesion Irrelevant Recurrent or new ocular disease Recurrent or positive
Any new site of disease: CNS or systemic

Note:—CRu indicates unconfirmed complete response; RPE, retinal pigment epithelium.