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. 2016 Nov;37(11):2033–2036. doi: 10.3174/ajnr.A4846

Etiologies of 3 territory diffusion-weighted lesions

No. Clinical/MR Imaging, DWI, Enhancement Features
Suspected etiology (n = 29)
    Trauma 1 History of trauma, imaging-associated sequelae of trauma, subarachnoid hemorrhage, shear pattern
    Demyelinating 1 Age, history of multiple sclerosis, periventricular/corpus callosum predilection
    Hypoxic-ischemic 5 Hypotension, deep nuclei and cortical ribbon involvement
    Metastasis 3 History of malignancy and/or ring or enhancing lesion
    Seizure 1 Seizures, deep nuclei and/or cortical ribbon enhancement
    HIV-related (n = 2)
        Toxoplasmosis 1 HIV, periventricular, ring, enhancing, target sign, rarely shows restricted diffusion
        Fungal abscess 1 HIV, ring, enhancing, numerous restricted-diffusion lesions
    Cerebral emboli (n = 10)
        Endocarditis 4 Fever, leukocytosis, murmur, ring, enhancing
        Air 1 Followed esophagogastroduodenoscopy
        Fat 1 Followed long bone fracture
        Atrial fibrillation 2 No source other than atrial fibrillation found
        Aortic atheroma 1 Significant arch atheroma noted
        Aortic dissection 1 Patient had concomitant aortic dissection
    Postoperative (n = 6)
        Aneurysm coiling 1 Symptoms developed postoperatively
        Cardiac surgery 4 Symptoms developed postoperatively
        Aortic aneurysm repair 1 Symptoms developed postoperatively
Not suspected (n = 10)
    Malignancy-related 9 Lung (n = 4), colon (n = 2), renal (n = 1), pancreas (n = 1), bladder (n = 1)
    Intravascular lymphoma 1 Proven by brain biopsy
Indeterminate (n = 2)
    Incomplete history 1 Lost to follow-up
    Multiple etiologies 1 Possible fat emboli vs Trousseau syndrome