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. 2017 Feb;38(2):250–256. doi: 10.3174/ajnr.A4999

Table 3:

Clinicoradiologic correlation using 3D-GE and 2D-SE normalized subcortical structure values obtained with FreeSurfer software

Subcortical Structure	FreeSurfer 3D-GE				FreeSurfer 2D-SE
	Disease Duration		EDSS		Disease Duration		EDSS
	r	P	ρ	P	r	P	ρ	P
Brain stem	−0.258	.123	−0.408^a	.012^a	−0.143	.400	−0.545^a	<.001^a
L thalamus	−0.249	.137	−0.268	.109	−0.301	.070	−0.313^b	.059^b
L caudate	−0.304^b	.068^b	−0.285^b	.088^b	−0.316^b	.057^b	−0.283	.090
L putamen	−0.443^a	.006^a	−0.494^a	.002^a	−0.466^a	.004^a	−0.510^a	.001^a
L pallidum	−0.489^a	.002^a	−0.409^a	.012^a	−0.315^b	.057^b	−0.404^a	.013^a
L hippocampus	−0.191	.256	−0.122	.472	−0.144	.397	−0.085	.615
L amygdala	−0.083	.627	−0.335^a	.043^a	0.001	.997	−0.141	.404
L accumbens	−0.332^a	.045^a	−0.418^a	.010^a	−0.358^a	.030^a	−0.096	.571
R thalamus	−0.409^a	.012^a	−0.402^a	.014^a	−0.386^a	.018^a	−0.376^a	.022^a
R caudate	−0.455^a	.005^a	−0.365^a	.02^a	−0.29^b	.074^b	−0.230	.171
R putamen	−0.505^a	.001^a	−0.490^a	.002^a	−0.472^a	.003^a	−0.494^a	.002^a
R pallidum	−0.459^a	.004^a	−0.395^a	.016^a	−0.220	.192	−0.28^b	.093^b
R hippocampus	−0.262	.118	−0.302^b	.069^b	−0.238	.157	−0.220	.190
R amygdala	−0.181	.285	−0.294^b	.077^b	−0.183	.279	−0.323^b	.051^b
R accumbens	−0.330^a	.046^a	−0.416^a	.011^a	−0.215	.202	−0.216	.199

Note:—r indicates the Pearson correlation coefficient; ρ, the Spearman correlation coefficient; L, left; R, right.

^a

Significant correlations.

^b

Trend toward a significant correlation.