Table 2:

Percentage changes of V_MY, V_EPW, R1, R2, and PD in plaques and periplaque white matter relative to normal-appearing white matter^a

	VMY (%)	VEPW (%)	R1 (%)	R2 (%)	PD (%)
Plaques	−61.59 ± 20.28b	13.82 × 103 ± 49.47 × 103b	−35.23 ± 13.93b	−21.06 ± 11.39b	23.37 ± 10.30b
PWM	−10.51 ± 11.41c	51.33 × 102 ± 155.31 × 102c	−6.08 ± 8.66c	−4.79 ± 6.79c	3.37 ± 4.24b

^aValues are mean ± SD. Of the 135 ROIs, 39 were discarded after calculating the percentage change of V_EPW relative to NAWM because the V_EPW of these ROIs was equivalent to zero in NAWM.

^bP < .001 in the percentage change for plaques relative to NAWM for comparison between each pair of metrics, except between R2 and PD (P = .31). Statistical analysis was performed for absolute values.

^cP < .001 in the percentage change for PWM relative to NAWM between V_EPW and other metrics, and between V_MY and R2 or PD, P < .05 between V_MY and R1, and P > .05 between R2 and R1 (.31) or PD (.30). Statistical analysis was performed for absolute values.