Table 4:
Regions in which VBM-DARTEL identified significantly reduced WM: comparisons between patients and normal controls
| Comparison and Brain Region | Talairach Coordinates |
t Value | |||
|---|---|---|---|---|---|
| Side | X | Y | Z | ||
| Controls > AD patients | |||||
| Medial temporal lobe | Lt | −25 | −27 | −16 | 6.30 |
| Medial temporal lobe | Rt | 30 | −27 | −7 | 5.88 |
| Fornix | Rt | 3 | −7 | 13 | 5.77 |
| Frontal lobe | Lt | −30 | 25 | 19 | 4.65 |
| Parieto-occipital lobe | Lt | −21 | −54 | 33 | 4.33 |
| DLB patients > AD patients | |||||
| Medial temporal lobe | Lt | −25 | −20 | −18 | 7.02 |
| Medial temporal lobe | Rt | 27 | −27 | −15 | 6.09 |
| Fornix | Lt | −1 | −6 | 11 | 4.69 |
| Frontal lobe | Rt | 6 | 23 | 53 | 3.63 |
| Temporal lobe | Rt | 45 | 2 | −22 | 3.45 |
| Medial parieto-occipital lobe | Rt | 9 | −50 | 22 | 3.28 |