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. 2021 Mar 9;2021:6624874. doi: 10.1155/2021/6624874

Table 2.

The modified O'Driscoll histologic score.

Characteristic Score
% hyaline cartilage 80–100 8
60–80 6
40-60 4
20-40 2
0-20 0
Structural characteristics
 Surface irregularity Smooth and intact 2
Fissures 1
Severe disruption, fibrillation 0
 Structural integrity Normal 2
Slight disruption, including cysts 1
Severe lack of integration 0
 Thickness 100% of normal adjacent cartilage 2
50% to 100% or thicker than normal 1
0–50% 0
 Bonding to adjacent cartilage Bonded at both ends of graft 2
Bonded at one end/partially both ends 1
Not bonded 0
Freedom from cellular changes of degeneration Normal cellularity, no clusters 2
Slight hypocellularity, <25% chondrocyte clusters 1
Moderate hypocellularity, >25% clusters 0
Freedom from degenerate changes in adjacent cartilage Normal cellularity, no clusters, normal staining 3
Normal cellularity, mild clusters, moderate staining 2
Mild or moderate hypocellularity, slight staining 1
Severe hypocellularity, slight staining 0
Reconstitution of subchondral bone Complete reconstitution 2
Greater than 50% reconstruction 1
50% or less reconstruction 0
Bonding of repair cartilage to de novo subchondral bone Complete and uninterrupted 2
<100% but >50% reconstruction 1
<50% complete 0
Safranin O staining >80% homogeneous positive stain 2
40%–80% homogeneous positive stain 1
<40% homogeneous positive stain 0
Total score Max 27