Table 2:
NPC detection—grading of the previous MRI and updated diagnostic performances of the previous MRI, endoscopy, and endoscopic biopsy based on long-term outcome at 3 years in 203 patients (78 with NPC and 125 without NPC)
| MRI | Endoscopy | Endoscopic Biopsya | |
|---|---|---|---|
| True-Positive | 78 | 69 | 73 |
| Grade 3 (n = 2); grade 4 (n = 76) | |||
| True-Negative | 115 | 118 | 125 |
| Grade 1 (n = 32); grade 2 (n = 83) | |||
| False-Positive | 10 | 7 | 0 |
| Grade 3 (n = 10); grade 4 (n = 0) | |||
| False-Negative | 0 | 9 | 5 |
| Grade 1 (n = 0); grade 2 (n = 0) | |||
| Sensitivity (%) | 100 | 88 | 94 |
| Specificity (%) | 92 | 94 | 100 |
| PPV (%) | 89 | 91 | 100 |
| NPV (%) | 100 | 93 | 96 |
| Accuracy (%) | 95 | 92 | 98 |
Note:—PPV indicates positive predictive value; NPV, negative predictive value.
a
Endoscopic biopsy is endoscopically directed biopsy obtained at the site of the abnormality seen at endoscopy or sampling biopsies obtained from the endoscopically normal nasopharynx.