Table 3:
Putative theories to explain elevated ICP in PTCa
Proximal Etiology | Result |
---|---|
Increased interstitial fluid (ISF) volume | Increased cerebral volume |
Increased blood volume | |
Increased tissue volume | |
Increased CSF production rate | Increased CSF volume |
Increased CSF outflow resistance | |
Loss of cerebral autoregulation | Increased cerebral arterial pressure |
Increased cerebral venous pressure | Increased venous blood volume and increased ISF |
Reduced CSF outflow and increased CSF volume |
(Adapted from Walker.10)