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. 2011 Dec;32(11):1986–1993. doi: 10.3174/ajnr.A2404

Table 3:

Putative theories to explain elevated ICP in PTCa

Proximal Etiology Result
Increased interstitial fluid (ISF) volume Increased cerebral volume
Increased blood volume
Increased tissue volume
Increased CSF production rate Increased CSF volume
Increased CSF outflow resistance
Loss of cerebral autoregulation Increased cerebral arterial pressure
Increased cerebral venous pressure Increased venous blood volume and increased ISF
Reduced CSF outflow and increased CSF volume
a

(Adapted from Walker.10)