Table 3:

Inter-rater agreement of parameters not included in the scoring tool

Parameter	κ	95% CI
Inter-rater agreement <0.6 or lower limit of 95% CI, <.5
Symmetric pattern	−0.04	−0.08–0.01
Ependymal enhancement	0.38	−0.15–0.91
Fingerlike + projection	0.46	0.10–0.82
Proportion of discrete lesions	0.39a	0.24–0.54
Not visualized on routine clinical brain imaging
Cervical spinal cord	0.72	0.42–1.0
Dot-dash sign	0.71	0.46–0.97
Cortical gray matter	0.36	0.15–0.58
Optic nerve lesion	0.48	−0.03–0.98
Optic nerve enhancement	0.82	0.50–1.0
Optic nerve sheath enhancement	–	–
Extraoptic fat enhancement	–	–
Extraoptic muscle enhancement	–	–
Perineural enhancement	–	–
Not contributory to differentiating ADEM, MS, and SV-pACNS
Frontal lobar location	0.60	0.36–0.85
Temporal lobar location	0.81	0.67–0.94
Parietal lobar location	0.80	0.66–0.94
Occipital lobar location	0.70	0.53–0.86
ACA vascular territory	0.56	0.37–0.75
MCA vascular territory	0.80	0.58–1.0
PCA vascular territory	0.64	0.47–0.82
Vertebrobasilar vascular territory	0.73	0.57–0.89
Cerebellar peduncle	0.76	0.59–0.93
Target lesion	0.78	0.62–0.94
Nodular leptomeningeal enhancement	–	–
Linear leptomeningeal enhancement	–	–
Dural enhancement	–	–
Supratentorial lesion enhancement	0.76	0.59–0.94
Infratentorial lesion enhancement	0.78	0.58–0.98

Note:—ACA indicates anterior cerebral artery; PCA, posterior cerebral artery; –, κ invalid due to low frequency of occurrence in ≥1 cell of the 2 × 2 table.

^aWeighted κ reported.