Table 1:

Demographic and clinical characteristics of the enrolled disease group subtypes

	HC (n = 73)	RRMS (n = 162)	SPMS (n = 66)
Age, median (IQR)	44 (17)	44 (16)	54.5 (9)
Sex
% Male	45.2	22.8	19.7
Male/female	33/40	37/125	13/53
EDSS, median (IQR) [# missing]		2 (1.5) [8]	6 (2) [2]
Disease duration, years; median (IQR)		9 (11)	19.5 (18)

Note:—Of the 228 patients with MS, 204 were on disease-modifying therapy. These included 68 patients on interferon beta-1a I.M., 23 on interferon beta 1a S.C., 1 on interferon beta 1b, 46 on glatiramer acetate, 50 on natalizumab, 3 on intravenous immunoglobulin, 4 on mycophenolate mofetil, 2 on azathioprine, 2 on combination therapy, and 1 on mitoxantrone; drug data for 4 patients were not recorded. IQR indicates interquartile range.