Table 3:
Summary of TBSS analysis
| Brain Region | FR-HS |
MR-HS |
FL-HS |
ML-HS |
||||
|---|---|---|---|---|---|---|---|---|
| FAp/FAc | MDp/MDc | FAp/FAc | MDp/MDc | FAp/FAc | MDp/MDc | FAp/FAc | MDp/MDc | |
| R cingulum | 0.23/0.28 | 0.85/0.82 | 0.21/0.29 | − | 0.31/0.35 | − | − | 1.00/0.89 |
| L cingulum | − | 0.84/0.73 | − | − | 0.24/0.34 | − | 0.30/0.35 | 1.00/0. 73 |
| R ATWM;ILF | 0.23/0.40 | 0.88/0.79 | 0.25/0.34 | 0.87/0.79 | 0.32/0.37 | 0.83/0.72 | 0.19/0.24 | − |
| L ATWM;ILF | 0.34/0.40 | 0.86/0.78 | − | − | 0.31/0.36 | 0.88/0.74 | 0.22/0.28 | 0.91/0.82 |
| R fornix | 0.29/0.33 | 1.45/1.33 | − | 1.69/1.48 | 0.34/0.39 | 1.70/1.32 | 0.28/0.44 | 1.87/1.57 |
| L fornix | − | − | 0.31/0.38 | − | 0.32/0.41 | 1.84/1.39 | 0.34/0.44 | 1.90/1.79 |
| R uncinate fasciculus | 0.30/0.43 | 0.84/0.79 | 0.36/0.45 | 0.84/0.77 | − | − | − | − |
| L uncinate fasciculus | − | − | − | − | 0.47/0.51 | 0.80/0.75 | 0.32/0.39 | 0.87/0.79 |
| CC genu | 0.36/0.59 | 0.76/0.68 | 0.64/0.78 | 0.88/0.70 | 0.38/0.49 | 0.78/0.74 | 0.40/0.56 | 1.07/0.77 |
| CC body | 0.44/0.52 | 1.12/0.92 | 0.38/0.51 | 1.69/1.29 | − | − | 0.46/0.68 | 1.09/0. 81 |
| R ALIC | 0.49/0.55 | 0.79/0.71 | 0.26/0.29 | 0.74/0.68 | 0.65/0.76 | 0.72/0.66 | 0.54/0.65 | 0.71/0.67 |
| R PLIC | 0.68/0.72 | 0.71/0.62 | 0.66/0.72 | − | 0.59/0.66 | 0.73/0.68 | − | − |
| L ALIC | − | − | − | − | 0.57/0.66 | 0.75/0.65 | 0.51/0.59 | 1.00/0.68 |
| L PLIC | − | − | 0.65/0.69 | − | 0.60/0.69 | 0.73/0.66 | − | − |
| R external capsule | 0.34/0.43 | 0.74/0.63 | 0.39/0.46 | − | − | − | 0.30/0.38 | − |
| L external capsule | 0.41/0.46 | 0.78/0.74 | 0.43/0.47 | − | 0.39/0.45 | 0.79/0.71 | 0.34/0.42 | 0.73/0.66 |
| R thalamus | 0.32/0.36 | 0.86/0.75 | 0.36/0.40 | 0.81/0.66 | 0.36/0.43 | 0.70/0.64 | 0.44/0.51 | 0.79/0.75 |
| L thalamus | 0.31/0.35 | 0.75/0.70 | 0.29/0.34 | 0.71/0.69 | 0.31/0.37 | 0.88/0.71 | 0.30/0.36 | 1.00/0.73 |
| R IFOF | 0.41/0.50 | − | 0.29/0.37 | 0.79/0.72 | − | − | 0.30/0.46 | − |
| L IFOF | − | − | 0.30/0.35 | − | 0.38/0.43 | 0.83/0.75 | 0.46/0.56 | 0.80/0.75 |
| R acoustic radiation | 0.45/0.49 | 0.79/0.69 | − | − | − | − | − | − |
Note:—The mean FA and MD (x10−3 mm2/s) values of significant clusters in patients along with those of control participants and corresponding WM regions are derived according to the Johns Hopkins University WM tractography atlas and the International Consortium for Brain Mapping DTI-81 WM atlas.
ATWM indicates anterior temporal lobe white matter; ALIC, anterior limb of the internal capsule; PLIC, posterior limb of the internal capsule; CC, corpus callosum; FAp/FAc, fractional anisotropy of the patients/fractional anisotropy of the controls; FL-HS, female patients with left HS; FR-HS, female patients with right HS; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; L, left; MDp/MDc, mean diffusivity of the patients/mean diffusivity of the controls; ML-HS, male patients with left HS; MR-HS, male patients with right HS; R, right; TBSS, tract-based spatial statistics.